US Food and Drug Administration Approves Kalydeco for Use in Eight Additional Mutations that Cause Cystic Fibrosis

-KALYDECO is the first medicine to treat the underlying cause of CF for people with specific mutations in the CFTR gene- -KALYDECO facilitates increased chloride transport by potentiating the channel-open probability (or gating) of the CFTR protein- -The eight additional … Continued

Vertex Announces Recent Progress and Upcoming Milestones in Research and Development Programs for Cystic Fibrosis

Enrollment complete for TRAFFIC and TRANSPORT Phase 3 studies of lumacaftor (VX-809) in combination with ivacaftor for people with two copies of the F508del mutation (homozygous); data expected in mid-2014 12-week Phase 2 study of VX-661 in combination with ivacaftor … Continued